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Haplogroup A2 is the most common haplogroup among the Inuit, Na-Dene, and many Amerind ethnic groups of North and Central America. Lineages belonging to haplogroup A2 also comprise the majority of the mtDNA pool of the Inuit and their neighbors, the Chukchis, in northeasternmost Siberia. [5] [6] [7]
Haplogroup A is a human Y-chromosome DNA haplogroup, which includes all living human Y chromosomes.Bearers of extant sub-clades of haplogroup A are almost exclusively found in Africa (or among the African diaspora), in contrast with haplogroup BT, bearers of which participated in the Out of Africa migration of early modern humans.
[12] [84] This suggests that 95% of Indigenous American mtDNA is descended from a minimal genetic founding female population, comprising sub-haplogroups A2, B2, C1b, C1c, C1d, and D1. [85] The remaining 5% is composed of the X2a, D2a, C4c, and D4h3a sub-haplogroups. [84] [85] X is one of the five mtDNA haplogroups found in Indigenous Americans.
(b) Counts of haplogroups in table format. For populations details, see 1000 Genomes Project#Human genome samples. In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree.
A haplotype is a group of alleles in an organism that are inherited together from a single parent, [1] [2] and a haplogroup (haploid from the Greek: ἁπλοῦς, haploûs, "onefold, simple" and English: group) is a group of similar haplotypes that share a common ancestor with a single-nucleotide polymorphism mutation. [3]
Haplogroup A2 is the main Native American haplogroup in Cuba (21.9% of the total sample), accounting for 67% of the Native American mtDNA gene pool. Regarding Y-chromosome haplogroups (male lineages), 78.8% of the sequences found in Cubans are of West Eurasian origin, 19.7% of African origin and 1.5% of East Asian origin.
(Data from studies conducted before 2004 may be inaccurate or a broad estimate, due to obsolete haplogroup naming systems – e.g. the former Haplogroup 2 included members of the relatively unrelated haplogroups known later as Haplogroup G and macrohaplogroup IJ [which comprises haplogroups I and J].)
The following articles are lists of human Y-chromosome DNA haplogroups found in populations around the world. Y-DNA haplogroups by ethnic group Y-DNA haplogroups in populations of Europe