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Canine epileptoid cramping syndrome. Canine epileptoid cramping syndrome (CECS), previously known as Spike's disease, is a hereditary dog disease initially found in Border Terriers and has since been documented in many other dog breeds including Labrador Retrievers and Chihuahuas, with similarities to canine epilepsy. Its cause is unknown. [1]
Epilepsy in animals is a group of neurological disorders characterized by seizures, caused by uncontrolled, abnormal bursts of electrical activity in the brain. They can start and stop very abruptly and last any amount of time from a few seconds to a few minutes. [ 1] Canine epilepsy is often genetic but epilepsy in cats and other pets is rarer ...
Imepitoin acts as a low- affinity (4,350–5,140 nM; relative to K i = 6.8 nM for diazepam and K i = 1.7 nM for clonazepam) partial agonist of the benzodiazepine site of the GABA A receptor (up to 12–21% of the maximal potentiation of diazepam, a full agonist of this site). [1] It is the first partial agonist to be approved for the treatment ...
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[68] [69] Dogs which display coprophagy, the consumption of feces, and also live in a household with a dog receiving levothyroxine treatment, may develop hyperthyroidism if they frequently eat the feces from the dog receiving levothyroxine treatment. [70] Hyperthyroidism may occur if a dog eats an excessive amount of thyroid gland tissue.
Treatment is with oral thyroid hormone supplementation. [105] [106] Lack of enough iodine in the diet can produce a form of hypothyroidism; without the proper amount of it, the thyroid gland fails to produce enough thyroid hormone. [102] Myxedema coma is a rare but serious aspect of the disease that is a medical emergency. [107]
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