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Fibrinolysis is a process that prevents blood clots from growing and becoming problematic. [1] Primary fibrinolysis is a normal body process, while secondary fibrinolysis is the breakdown of clots due to a medicine, a medical disorder, or some other cause. [2] In fibrinolysis, a fibrin clot, the product of coagulation, is broken down. [3]
Animation of the shoulder joint. The muscles shown are subscapularis muscle (at right), infraspinatus muscle (at top left), teres minor muscle (at bottom left) The movement of the scapula across the rib cage in relation to the humerus is known as the scapulohumeral rhythm, and this helps to achieve a further range of movement. This range can be ...
Thrombolysis, also called fibrinolytic therapy, is the breakdown of blood clots formed in blood vessels, using medication.It is used in ST elevation myocardial infarction, stroke, and in cases of severe venous thromboembolism (massive pulmonary embolism or extensive deep vein thrombosis).
Fibrinolysis syndrome is characterized by an acute hemorrhagic state brought about by inability of the blood to clot, with massive hemorrhages into the skin producing blackish, purplish swellings and sloughing.
The most important ligament involved in shoulder joint stability is the Inferior Glenohumeral Ligament. During abduction of the arm, the middle and inferior ligaments become taut while the superior ligament relaxes. The radius of curvature of the head of the humerus is greater superiorly than inferiorly, which further stretches these ligaments ...
The rhomboid major is a skeletal muscle of the back that connects the scapula with the vertebrae of the spinal column. [1] It originates from the spinous processes of the thoracic vertebrae T2–T5 and supraspinous ligament; it inserts onto the lower portion of the medial border of the scapula. [2]
A special situation with temporarily enhanced fibrinolysis is thrombolytic therapy with drugs which activate plasminogen, e.g. for use in acute ischemic events or in patients with stroke. In patients with severe trauma, hyperfibrinolysis is associated with poor outcome. [7]
Thrombolysis is most effective in the first 2 hours. After 12 hours, the risk of intracranial bleeding associated with thrombolytic therapy outweighs any benefit. [ 3 ] [ 6 ] [ 7 ] Because irreversible injury occurs within 2–4 hours of the infarction, there is a limited window of time available for reperfusion to work.