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4-Chloroaniline is an organochlorine compound with the formula ClC 6 H 4 NH 2. This pale yellow solid is one of the three isomers of chloroaniline . Preparation
Chloroaniline may refer to any of three isomeric chemical compounds: 2-Chloroaniline [Wikidata] 3-Chloroaniline; 4-Chloroaniline This page was last edited on 9 ...
4,7-Dichloroquinoline was first reported in a patent filed by IG Farben in 1937. [2] However, its synthesis was not investigated in detail until chloroquine was developed as an antimalarial drug. [ 3 ] : 130–132 A route to the intermediate starting from 3-chloroaniline was developed by chemists at Winthrop Chemical Co .
4-Chloro-o-toluidine (4-COT, 4-chloro-2-methylaniline) is the organic compound with the formula CH 3 C 6 H 3 Cl(NH 2). It is a colorless solid. The compound is produced as an intermediate to the pesticide chlordimeform and a precursor to some azo dyes. Production has declined after it was shown to be highly carcinogenic.
4,4′-Methylenebis(2-chloroaniline) (also known as MOCA, MBOCA, and bisamine) is a substance used as a curing agent in polyurethane production. [3] MOCA is an aromatic amine which is structurally similar to benzidine , a known human bladder carcinogen.
4-Nitroaniline is produced industrially via the amination of 4-nitrochlorobenzene: [3] ClC 6 H 4 NO 2 + 2 NH 3 → H 2 NC 6 H 4 NO 2 + NH 4 Cl. Below is a laboratory synthesis of 4-nitroaniline from aniline. The key step in this reaction sequence is an electrophilic aromatic substitution to install the nitro group para to the amino group. The ...
4-Fluoroaniline can be prepared by the hydrogenation of 4-nitrofluorobenzene. [2] It is a common building block in medicinal chemistry and related fields. [3] For example, it is a precursor to the fungicide fluoroimide or the fentanyl analogue parafluorofentanyl. It has also been evaluated for the production of ligands for homogeneous catalysis ...
4-Chlorobenzaldehyde (o-Chlorobenzaldehyde) is an organic compound with the formula ClC 5 H 4 CHO. It is one of three isomeric monochlorinated benzaldehydes . Preparation
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