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In October 2024, the Committee for Veterinary Medicinal Products of the European Medicines Agency adopted a positive opinion, recommending the granting of a marketing authorization for the veterinary medicinal product Duotic, Ear gel, intended for dogs. [3] The applicant for this veterinary medicinal product is Dechra Regulatory B.V. [3]
Examination of a dog's ear canal with an otoscope as performed by a veterinarian In mild cases, a product with anti-inflammatory, anti-fungal and anti-bacterial ingredients are often employed. In more severe cases, ear cleaning under sedation or anesthesia may be required and evaluation for otitis media may be indicated.
pimobendan – phosphodiesterase 3 inhibitor used to manage heart failure in dogs; pirlimycin – antimicrobial; ponazuril – anticoccidial; praziquantel – treatment of infestations of the tapeworms Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus; prazosin – sympatholytic used in hypertension and abnormal muscle contractions
Zeltia is a former Spanish pharmaceutical company which operated through a variety of subsidiaries in the pharmaceutical and chemical industries. As of 2007, Zeltia's research activities in the pharmaceutical area had not resulted in a marketed product.
Because dogs are ten times more likely to become infected from the environment than humans, they are considered to be sentinels for the disease. Treatment requires a minimum 60–90-day course of oral antifungal medication or in severe cases intravenous antifungal injections. [10]
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [ 3 ] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
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