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Two years later, Bayer created acetylsalicylic acid, which they marketed around the world under the brand name "Aspirin". [ 1 ] : 27 The drug was sold widely in the first half of the twentieth century, both by Bayer and by competing drug manufacturers.
Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [10] For pain or fever, effects typically begin within 30 minutes. [10] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [10] One common adverse effect is an upset ...
Additionally, aspirin induces the formation of NO-radicals in the body, which have been shown in mice to have an independent mechanism of reducing inflammation. This reduces leukocyte adhesion, which is an important step in immune response to infection. There is currently insufficient evidence to show that aspirin helps to fight infection. [18]
Salicylic acid has long been a key starting material for making acetylsalicylic acid (ASA or aspirin). [8] ASA is prepared by the acetylation of salicylic acid with the acetyl group from acetic anhydride or acetyl chloride. [17] ASA is the standard to which all the other non-steroidal anti-inflammatory drugs are compared. In veterinary medicine ...
Felix Hoffmann was born on 21 January 1868 in Ludwigsburg, Germany, the son of an industrialist.In 1889, he started studying chemistry at the Ludwig Maximilian University of Munich to study pharmacy and ended it in 1890 with the pharmaceutical state exam.
English: A diagram showing the chemical synthesis of aspirin. العربية: ... This structural formula was created with BKchem-Inkscape. Licensing.
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Arthur Eichengrün, a Bayer chemist, said he was the first to discover an aspirin formulation that did not have the unpleasant side effects of nausea and gastric pain. He also said he had invented the name aspirin and was the first person to use the new formulation to