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  2. Combined drug intoxication - Wikipedia

    en.wikipedia.org/wiki/Combined_drug_intoxication

    In general, the simultaneous use of multiple drugs should be carefully monitored by a qualified individual such as board certified and licensed medical doctor, either an MD or DO. Close association between prescribing physicians and pharmacies, along with the computerization of prescriptions and patients' medical histories, aim to avoid the ...

  3. Long-term effects of cannabis - Wikipedia

    en.wikipedia.org/wiki/Long-term_effects_of_cannabis

    However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances. A study looking at associations between drug injection and cannabis use in street-involved youth found that cannabis use was associated with slower time to injection initiation. [68]

  4. Polysubstance use - Wikipedia

    en.wikipedia.org/wiki/Polysubstance_use

    Combined drug intoxication use often carries with it more risk than use of a single drug, due to an increase in side effects, and drug synergy. The potentiating effect of one drug on another is sometimes considerable and here the licit drugs and medicines – such as alcohol, nicotine and antidepressants – have to be considered in conjunction ...

  5. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    The third edition, published in 1980, was the first to recognize substance abuse (including drug abuse) and substance dependence as conditions separate from substance abuse alone, bringing in social and cultural factors. The definition of dependence emphasised tolerance to drugs, and withdrawal from them as key components to diagnosis, whereas ...

  6. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    Concerning the 2017 data in the charts below, deaths from the various drugs add up to more than 70,200 because multiple drugs are involved in many of the deaths. [2] According to the National Safety Council, the lifetime odds of dying from an overdose in the United States is 1 in 96. [68] Drug overdose deaths in the US per 100,000 people by state.

  7. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  8. Drug overdose - Wikipedia

    en.wikipedia.org/wiki/Drug_overdose

    The 22,767 deaths relating to prescription drug overdose in 2013, 16,235 (71.3%) involved opioid painkillers, and 6,973 (30.6%) involved benzodiazepines. Drug misuse and abuse caused about 2.5 million emergency department (ED) visits in 2011. Of these, more than 1.4 million ED visits were related to prescription drugs.

  9. War on drugs - Wikipedia

    en.wikipedia.org/wiki/War_on_drugs

    War on drugs A U.S. government PSA from the Alcohol, Drug Abuse, and Mental Health Administration with a photo image of two marijuana cigarettes and a "Just Say No" slogan Date June 17, 1971 – present (53 years, 7 months and 1 week) Location Global Status Ongoing, widely viewed as a policy failure Belligerents United States US law enforcement Drug Enforcement Administration US Armed Forces ...