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Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative.It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects.
[4] [5] [2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2] Symptoms in moderate cases include high body temperature, agitation, increased reflexes, tremor, sweating, dilated pupils, and diarrhea. [1] [2] In severe cases, body temperature can increase to greater than 41.1 °C (106.0 °F). [2]
In addition, they may cause the syncope by lowering the blood pressure and heart rate. [ 23 ] [ 24 ] Medications which may be effective include: CNS stimulants [ 25 ] fludrocortisone , midodrine , SSRIs [ 26 ] such as paroxetine or sertraline , disopyramide , and, in health-care settings where a syncope is anticipated, atropine or epinephrine ...
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.
[1] [3] Issues with the heart and blood vessels are the cause in about 10% and typically the most serious while neurally mediated is the most common. [1] Heart related causes may include an abnormal heart rhythm, problems with the heart valves or heart muscle and blockages of blood vessels from a pulmonary embolism or aortic dissection among ...
A new study says that type 2 diabetes medications GLP-1 agonists and SGLT2 inhibitors may help lower a stroke survivor’s risk of experiencing a subsequent stroke, heart attack, or death ...
Structural heart disease, such as heart failure, myocardial infarction, and left ventricular hypertrophy, are also risk factors. Diuretic-induced hypokalemia and/or hypomagnesemia taken for heart failure can induce proarrthymia. The ischemia that results from myocardial infarctions also induce QT prolongation. [citation needed]
Generalized vasoconstriction usually results in an increase in systemic blood pressure, but it may also occur in specific tissues, causing a localized reduction in blood flow. The extent of vasoconstriction may be slight or severe depending on the substance or circumstance. Many vasoconstrictors also cause pupil dilation.