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The signs and symptoms of ischemia vary, as they can occur anywhere in the body and depend on the degree to which blood flow is interrupted. [4] For example, clinical manifestations of acute limb ischemia (which can be summarized as the "six P's") include pain, pallor, pulseless, paresthesia, paralysis, and poikilothermia.
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.
On the other hand, when the symptoms exceed 14 days, [3] it is called critical limb ischemia (CLI). CLI is the end stage of peripheral vascular disease where there is still some collateral circulation (alternate circulation pathways) that bring some blood flow (although inadequate) to the distal parts of the limbs. [2]
This is an incomplete list, which may never be able to satisfy certain standards for completion.. There are many conditions of or affecting the human circulatory system — the biological system that includes the pumping and channeling of blood to and from the body and lungs with heart, blood and blood vessels.
Shock is the state of insufficient blood flow to the tissues of the body as a result of problems with the circulatory system. Initial symptoms of shock may include weakness, tachycardia, hyperventilation, sweating, anxiety, and increased thirst. [1] This may be followed by confusion, unconsciousness, or cardiac arrest, as complications worsen. [1]
Illustration of how the buildup of lipids cause a blockage of blood flow to the portion of the artery below the narrowing. Peripheral arterial disease is considered to be a set of chronic or acute syndromes, generally derived from the presence of occlusive arterial disease, which causes inadequate blood flow to the limbs. [51] [52]
[1] [3] Issues with the heart and blood vessels are the cause in about 10% and typically the most serious while neurally mediated is the most common. [1] Heart related causes may include an abnormal heart rhythm, problems with the heart valves or heart muscle and blockages of blood vessels from a pulmonary embolism or aortic dissection among ...
White blood cells, carried to the area by the newly returning blood, release a host of inflammatory factors such as interleukins as well as free radicals in response to tissue damage. [2] The restored blood flow reintroduces oxygen within cells that damages cellular proteins, DNA, and the plasma membrane. Damage to the cell's membrane may in ...