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In Egypt, vaginal cream containing clindamycin produced by Biopharmgroup sold as Vagiclind indicated for vaginosis. [citation needed] Clindamycin is available as a generic drug, for both systemic (oral and intravenous) and topical use. [32] (The exception is the vaginal suppository, which is not available as a generic in the US [73]).
Clindamycin/benzoyl peroxide, sold under the brand name Benzaclin among others, is a topical gel used for the treatment of acne. [7] It is a fixed-dose combination of clindamycin, as the phosphate, an antibiotic; and benzoyl peroxide, an antiseptic. [7] Common side effects include peeling, itching, and dryness of the skin where the gel was ...
Topical gels are commonly used as sustained release dosage forms. [5] [9] Usage of the sustained release dosage form reduces the administration of recurrent doses while maintaining serum dose levels at the therapeutic range (difference between toxic and therapeutic doses), hence improving patient compliance. [5]
It is commonly available without a prescription in various dosage forms, such as a topical cream, ointment, or vaginal suppository. [2] [7] It is also available as an oral troche or throat lozenge as a prescription only. Topically, clotrimazole is used for vulvovaginal candidiasis (yeast infection) or yeast infections of the skin. For ...
However, vaginal rings have the potential to provide long-term controlled release of microbicide drugs. Long-acting formulations, like vaginal rings, are potentially advantageous since they could be easy to use, requiring replacement only once a month. This ease of use could prove very important to make sure that products are used properly.
Administering a vaginal tablet without an applicator. Intravaginal administration is a route of administration where the substance is applied inside the vagina . Pharmacologically , it has the potential advantage to result in effects primarily in the vagina or nearby structures (such as the vaginal portion of cervix ) with limited systemic ...
Cream. A cream is a preparation usually for application to the skin.Creams for application to mucous membranes such as those of the rectum or vagina are also used. Creams may be considered pharmaceutical products, since even cosmetic creams are manufactured using techniques developed by pharmacy and unmedicated creams are highly used in a variety of skin conditions (dermatoses).
The vaginal flora consists of those organisms which generally do not cause symptoms and is dominated mainly by Lactobacillus species. [13] Disruption of the normal flora can cause a vaginal yeast infection. Vaginal yeast infection can affect women of all ages and is very common. The yeast Candida albicans is the most common cause of vaginitis ...
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