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Minoxidil is a medication used for the treatment of high blood pressure and pattern hair loss. [ 5 ] [ 6 ] [ 7 ] It is an antihypertensive and a vasodilator . [ 10 ] It is available as a generic medication by prescription in oral tablet form and over-the-counter as a topical liquid or foam.
In its early days, before this topical treatment was developed and promoted as a mainstream hair loss treatment, minoxidil was developed as a treatment for hypertension (high blood pressure).
A 2002 study compared 5% and 2% minoxidil. Almost 400 men with male pattern baldness used either the 2% or 5% solution or a placebo twice a day for 48 weeks. ... Low blood pressure or high heart ...
Oral minoxidil is FDA-approved for high blood pressure but is sometimes used off-label for hair loss. They produce similar results. Clinical trials show the two forms of minoxidil work comparably.
Minoxidil sulfate is a sulfate ester of minoxidil, not a sulfate salt of the compound. [3] However, minoxidil sulfate forms an inner salt , which makes it more hydrophobic than minoxidil. [ 3 ] This is in contrast to most sulfate esters, which are usually more hydrophilic than their non-ester forms. [ 3 ]
Minoxidil can also negatively interact with alcohol and lower your blood pressure. Additionally, it may not be safe to use minoxidil, even at a low dose, if you have: Congestive heart failure
Research also suggests that oral minoxidil is generally safe and effective for men with hair loss, although it should be used with caution in men with hypertension (high blood pressure) or heart ...
Originally used to treat high blood pressure, minoxidil produced an unexpected side effect: healthy hair growth. The active ingredient in Rogaine, minoxidil is a topical solution that is applied ...