Search results
Results from the WOW.Com Content Network
Transcytosis (also known as cytopempsis) [1] is a type of transcellular transport in which various macromolecules are transported across the interior of a cell. Macromolecules are captured in vesicles on one side of the cell, drawn across the cell, and ejected on the other side.
The symptoms of TACO can include shortness of breath , low blood oxygen levels , leg swelling (peripheral edema), high blood pressure (hypertension), and a high heart rate (tachycardia). [ 3 ] It can occur due to a rapid transfusion of a large volume of blood but can also occur during a single red blood cell transfusion (about 15% of cases). [ 2 ]
Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
One study found that men with moderate-to-high levels of exhaustion had a 2.7-fold increased risk of heart attack within five years and a 2.25 higher risk within ten years. The study also found a ...
Transcytosis can also be taken advantage of by pathogenic molecules and organisms. Several studies have shown that bacterium can easily enter intestinal lumen through transcytosis of goblet cells. [7] Other studies, however, are exploring the idea that transcytosis may play a role in allowing medications to cross the blood-brain barrier.
Polycythemia is defined as serum hematocrit (Hct) or hemoglobin (HgB) exceeding normal ranges expected for age and sex, typically Hct >49% in healthy adult men and >48% in women, or HgB >16.5 g/dL in men or >16.0 g/dL in women. [8] The definition is different for neonates and varies by age in children. [9] [10]
The activity of this enzyme is usually reduced by 50% in all tissues in people with the inherited form of the condition. [citation needed] Nongenetic factors such as excess iron or partially genetic factors such as alcohol use disorder and others listed above can increase the demand for heme and the enzymes required to make heme. The ...
A new study finds that in about one in 10 cases of multiple sclerosis, the body makes a distinct set of antibodies years before symptoms emerge. (Getty Images) (Md Babul Hosen via Getty Images)