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Figure 1. An interphase nucleus (left) and a set of mitotic chromosomes (right) from human tissue culture cells. Bar, 10 μm. Condensins are large protein complexes that play a central role in chromosome assembly and segregation during mitosis and meiosis (Figure 1).
During mitosis, the chromosomes, which have already duplicated during interphase, condense and attach to spindle fibers that pull one copy of each chromosome to opposite sides of the cell. [4] The result is two genetically identical daughter nuclei. The rest of the cell may then continue to divide by cytokinesis to produce two daughter cells. [5]
Various DNA stains are used to treat cells such that condensing chromosomes can be visualized as the move through prophase. [4] The giemsa G-banding technique is commonly used to identify mammalian chromosomes, but utilizing the technology on plant cells was originally difficult due to the high degree of chromosome compaction in plant cells.
The hierarchical folding model of chromosome condensation. Premature chromosome condensation (PCC), also known as premature mitosis, occurs in eukaryotic organisms when mitotic cells fuse with interphase cells. [1] Chromatin, a substance that contains genetic material such as DNA, is normally found in a loose bundle inside a cell's nucleus.
The thick lines are chromosomes, and the thin blue lines are fibers pulling on the chromosomes and pushing the ends of the cell apart. The cell cycle in eukaryotes: I = Interphase, M = Mitosis, G 0 = Gap 0, G 1 = Gap 1, G 2 = Gap 2, S = Synthesis, G 3 = Gap 3. Cell division is the process by which a parent cell divides into two daughter cells. [1]
Condensation of long double-helical DNAs is a sharp phase transition, which takes place within a narrow interval of condensing agent concentrations.[ref] Since the double helices come very closely to each other in the condensed phase, this leads to the restructuring of water molecules, which gives rise to the so-called hydration forces.[ref] To ...
Higher-level DNA supercoiling of the 30 nm fiber produces the metaphase chromosome (during mitosis and meiosis). Many organisms, however, do not follow this organization scheme. For example, spermatozoa and avian red blood cells have more tightly packed chromatin than most eukaryotic cells, and trypanosomatid protozoa do not condense their ...
Stages of early mitosis in a vertebrate cell with micrographs of chromatids Metaphase (from Ancient Greek μετα- ( meta- ) beyond, above, transcending and from Ancient Greek φάσις (phásis) 'appearance') is a stage of mitosis in the eukaryotic cell cycle in which chromosomes are at their second-most condensed and coiled stage (they are ...