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Retinyl palmitate, or vitamin A palmitate, is the ester of retinol and palmitic acid, with formula C 36 H 60 O 2. It is the most abundant form of vitamin A storage in animals. [2] An alternate spelling, retinol palmitate, which violates the -yl organic chemical naming convention for esters, is also frequently seen. [citation needed]
Retinol-binding proteins (RBP) are a family of proteins with diverse functions. They are carrier proteins that bind retinol.Assessment of retinol-binding protein is used to determine visceral protein mass in health-related nutritional studies.
Retinyl esters can be distinguished from retinol in serum and other tissues and quantified with the use of methods such as high-performance liquid chromatography. [21] Elevated amounts of retinyl ester (i.e., >10% of total circulating vitamin A) in the fasting state have been used as markers for chronic hypervitaminosis A in humans and monkeys ...
Vitamin A is a fat-soluble vitamin that is an essential nutrient.The term "vitamin A" encompasses a group of chemically related organic compounds that includes retinol, retinyl esters, and several provitamin (precursor) carotenoids, most notably β-carotene (beta-carotene).
Retinol, also called vitamin A 1, is a fat-soluble vitamin in the vitamin A family that is found in food and used as a dietary supplement. [3] Retinol or other forms of vitamin A are needed for vision, cellular development, maintenance of skin and mucous membranes, immune function and reproductive development. [3]
In enzymology, a retinyl-palmitate esterase (EC 3.1.1.21) is an enzyme that catalyzes the chemical reaction. retinyl palmitate + H 2 O ⇌ {\displaystyle \rightleftharpoons } retinol + palmitate Thus, the two substrates of this enzyme are retinyl palmitate and H 2 O , whereas its two products are retinol and palmitate .
an all-trans-retinyl ester + H 2 O = 11-cis-retinol + a fatty acid. This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is all-trans-retinyl ester acylhydrolase, 11-cis retinol-forming. This enzyme participates in retinol metabolism.
The major source of retinoids in human diet are plant pigments such as carotenes and retinyl esters derived from animal sources. [15] Retinyl esters are transported through the chylomicron pathway to the liver or fat tissue while retinol or carotenes are transported from the enterocytes to the liver and are processed into retinyl esters by LRAT ...