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  2. Ribavirin - Wikipedia

    en.wikipedia.org/wiki/Ribavirin

    Its use during pregnancy can bring harm to the developing fetus. [1] Effective birth control is recommended for both males and females for at least seven months during and after use. [8] The mechanism of action of ribavirin is not entirely clear. [1] Ribavirin was patented in 1971 and approved for medical use in 1986. [9]

  3. Topical antifungal - Wikipedia

    en.wikipedia.org/wiki/Topical_antifungal

    The chemical structure of ergosterol. The general mechanism of action for topical antifungal drugs is the disruption of the cell membrane.The unique components found in fungal cell membranes are usually the drug targets of antifungal drugs, in particular ergosterol.

  4. Peginterferon alfa-2a - Wikipedia

    en.wikipedia.org/wiki/Peginterferon_alfa-2a

    Use with ribavirin is not recommended during pregnancy. [3] Pegylated interferon alfa-2a is in the alpha interferon family of medications. [3] It is pegylated to protect the molecule from breakdown. [6] Pegylated interferon alfa-2a was approved for medical use in the United States in 2002. [3]

  5. Lymphocytic choriomeningitis - Wikipedia

    en.wikipedia.org/wiki/Lymphocytic_choriomeningitis

    Early and intravenous ribavirin treatment is required for maximal efficacy, and it can produce considerable side effects. [27] Ribavirin has not been evaluated yet in controlled clinical trials. [citation needed] Use of ribavirin during pregnancy is generally not recommended, as some studies indicate the possibility of teratogenic effects. If ...

  6. Incyte skin disease cream for children meets main goal in ...

    www.aol.com/news/incyte-skin-disease-cream...

    Opzelura showed statistically significant improvement in the chronic skin condition, atopic dermatitis, on a disease severity scale compared to patients treated with non-medicated cream. It ...

  7. Taribavirin - Wikipedia

    en.wikipedia.org/wiki/Taribavirin

    Taribavirin has better liver-targeting than ribavirin, and has a shorter life in the body due to less penetration and storage in red blood cells. It is expected eventually to be the drug of choice for viral hepatitis syndromes in which ribavirin is active. These include hepatitis C and perhaps also hepatitis B and yellow fever.

  8. Antiviral drug - Wikipedia

    en.wikipedia.org/wiki/Antiviral_drug

    Viruses can also be screened for resistance to drugs before treatment is started. This minimizes exposure to unnecessary antivirals and ensures that an effective medication is being used. This may improve patient outcomes and could help detect new resistance mutations during routine scanning for known mutants. [53]

  9. Simeprevir - Wikipedia

    en.wikipedia.org/wiki/Simeprevir

    During pregnancy when used with ribavirin it may cause harm to the baby while when used with sofosbuvir its safety is unclear. [2] [6] Simeprevir is a HCV protease inhibitor. [2] Simeprevir was developed by Medivir AB and Janssen Pharmaceutica. [7] It was approved for medical use in the United States in 2013. [8]

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