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Pain in childbirth also serves to protect the child and the mother during the childbirth process. Pain has some function roles to warn the body of potential danger or to the presence of injury. In the case of pregnancy, it can help the pregnant individual to detect any danger to the child, as well as adjusting to an optimal position for childbirth.
Opioids can cross both the placental and blood-brain barriers, which poses risks to fetuses and newborns exposed to these drugs before birth. This exposure to opioids during pregnancy can lead to potential obstetric complications, including spontaneous abortion, abruption of the placenta, pre-eclampsia, prelabor rupture of membranes, and fetal death.
In contrast, paracetamol (acetaminophen) is regarded as being safe and well tolerated during pregnancy, but Leffers et al. released a study in 2010, indicating that there may be associated male infertility in the unborn. [92] [93] Doses should be taken as prescribed, due to risk of liver toxicity with overdoses. [94]
Painkillers, also known as opioids, are the most frequently abused ones, per data from the New York State Department of Health. These include morphine, codeine, oxycodone and hydrocodone, with ...
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Use during pregnancy may harm the fetus. [1] Use with alcohol is not recommended. [3] Hydrocodone works by binding to the mu-opioid receptor. [1]
Metamizole or dipyrone is a painkiller, spasm reliever, and fever reliever drug. It is most commonly given by mouth or by intravenous infusion. [13] [11] [14] It belongs to the ampyrone sulfonate family of medicines and was patented in 1922. Metamizole is marketed under various trade names.