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A biofilm is a syntrophic community of microorganisms in which cells stick to each other and often also to a surface. [2] [3] These adherent cells become embedded within a slimy extracellular matrix that is composed of extracellular polymeric substances (EPSs).
EPSs are mostly composed of polysaccharides (exopolysaccharides) and proteins, but include other macromolecules such as DNA, lipids and humic substances. EPSs are the construction material of bacterial settlements and either remain attached to the cell's outer surface, or are secreted into its growth medium.
The bacterial capsule is a large structure common to many bacteria. [1] It is a polysaccharide layer that lies outside the cell envelope, and is thus deemed part of the outer envelope of a bacterial cell. It is a well-organized layer, not easily washed off, and it can be the cause of various diseases. [2] [3]
Biofilms. Bacteria often attach to surfaces and form dense aggregations called biofilms [ 51 ] and larger formations known as microbial mats . [ 52 ] These biofilms and mats can range from a few micrometres in thickness to up to half a metre in depth, and may contain multiple species of bacteria, protists and archaea.
A microbial mat is a multi-layered sheet or biofilm of microbial colonies, composed of mainly bacteria and/or archaea. Microbial mats grow at interfaces between different types of material, mostly on submerged or moist surfaces, but a few survive in deserts. [1] A few are found as endosymbionts of animals.
Rather, a biofilm is made up of an array of microorganisms that come together to form a cohesive biofilm. [7] Although, there are homogeneous biofilms that can form. For example, the plaque that forms on the surfaces of teeth is caused by a biofilm formation of primarily Streptococcus mutans and the slow breakdown of tooth enamel. [8] [9]
This represented an operational decline of 3.2% that was primarily due to lower Juvederm sales as Botox cosmetic sales were roughly flat on an operational basis.
Humoral immunity is also referred to as antibody-mediated immunity. The study of the molecular and cellular components that form the immune system , including their function and interaction, is the central science of immunology .
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