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  2. Teriflunomide - Wikipedia

    en.wikipedia.org/wiki/Teriflunomide

    Teriflunomide is an immunomodulatory drug inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase. It is uncertain whether this explains its effect on MS lesions. It is uncertain whether this explains its effect on MS lesions.

  3. Tovorafenib - Wikipedia

    en.wikipedia.org/wiki/Tovorafenib

    Tovorafenib, sold under the brand name Ojemda, is a medication used for the treatment of glioma. [1] [2] It is a kinase inhibitor.[1]The most common adverse reactions include rash, hair color changes, fatigue, viral infection, vomiting, headache, hemorrhage, pyrexia, dry skin, constipation, nausea, dermatitis acneiform, and upper respiratory tract infection. [3]

  4. Disruptive mood dysregulation disorder - Wikipedia

    en.wikipedia.org/wiki/Disruptive_mood...

    Disruptive mood dysregulation disorder (DMDD) is a mental disorder in children and adolescents characterized by a persistently irritable or angry mood and frequent temper outbursts that are disproportionate to the situation and significantly more severe than the typical reaction of same-aged peers.

  5. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Treatment of adults with previously treated, unresectable or metastatic HER2-positive (IHC3+) biliary tract cancer as detected by an FDA approved test [2] Zenocutuzumab: Treatment of adults with advanced, unresectable or metastatic non-small cell lung cancer harboring a neuregulin 1 (NRG1) gene fusion with disease progression on or after prior ...

  6. Leflunomide - Wikipedia

    en.wikipedia.org/wiki/Leflunomide

    Leflunomide is an immunomodulatory drug that achieves its effects by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH), which plays a key role in the de novo synthesis of uridine monophosphate (rUMP), which is required for the synthesis of DNA and RNA.

  7. Spectrum Health Systems announced in February that its mobile treatment service program is the first in the state to provide all three medications for opioid use disorder — methadone, suboxone ...

  8. US approves first gene therapy for children with rare genetic ...

    www.aol.com/news/us-approves-first-gene-therapy...

    The one-time therapy, branded as Lenmeldy in the U.S., is approved for children in certain stages of disease progression, the Food and Drug Administration (FDA) said. US approves first gene ...

  9. Dutasteride - Wikipedia

    en.wikipedia.org/wiki/Dutasteride

    Dutasteride is approved for the treatment of male androgenetic alopecia in South Korea and Japan at a dosage of 0.5 mg per day. [6] [17] Several studies have found it to induce hair regrowth in men more rapidly and to a greater extent than even the highest approved dosage of finasteride.