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The first human cases of COVID-19 occurred in Wuhan, People's Republic of China, on or about 17 November 2019. [2] The first confirmed human case in the United States was on 19 January 2020. The World Health Organization declared the COVID-19 outbreak a Public Health Emergency of International Concern (PHEIC) on 30 January 2020, and first ...
All RMPs for COVID‑19 vaccines will be published on the EMA's website. [136] The EMA published guidance for developers of potential COVID‑19 vaccines on the clinical evidence to include in marketing authorization applications. [137] In November 2020, the CHMP started a rolling review of the Moderna vaccine for COVID‑19 known as mRNA-1273 ...
BioNTech initiated "Project Lightspeed" in January 2020 to develop an mRNA-based COVID-19 vaccine, just days after the SARS-Cov-2 genetic sequence was first made public. [30] In March 2020, BioNTech partnered with Fosun Pharma for mainland China and the special administrative regions of Hong Kong and Macau and Pfizer for the rest of the world ...
This article documents the chronology and epidemiology of SARS-CoV-2 in 2019, the virus that causes coronavirus disease 2019 and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 known to have been identified were in Wuhan , Hubei , China , in December 2019.
On January 20, Chinese authorities announced the confirmation that human-to-human transmission of the coronavirus had already occurred. [19] [20]The first recorded U.S. case of the new virus was also reported on January 20, in a 35-year-old American citizen traveling from Wuhan, China, to his home in Washington state.
The COVID-19 mRNA vaccines from Moderna and Pfizer–BioNTech had short-term efficacy rates of over 90 percent against the original SARS-CoV-2 virus. Prior to mRNA, drug trials on pathogens other than COVID-19 were not effective and had to be abandoned in the early phases of trials. The reason for the efficacy of the new mRNA vaccines is not clear.
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The United States and South Korea each reported their first confirmed case of the coronavirus to the World Health Organization on 20 January. [ 110 ] [ 111 ] US CDC developed its own testing kit after China shared the genetic sequence on 10 January and deployed it to detect the first coronavirus case.