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Alcohol dehydrogenase [NADP+] also known as aldehyde reductase or aldo-keto reductase family 1 member A1 is an enzyme that in humans is encoded by the AKR1A1 gene. [ 5 ] [ 6 ] [ 7 ] AKR1A1 belongs to the aldo-keto reductase (AKR) superfamily.