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These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Individual dogs of any breed can have a profound reaction characterized by hypotension, especially if there is an underlying heart problem. In giant-breed dogs and sighthounds, the sedative effects of acepromazine may last for 12–24 hours, which is much longer than the usual 3–4 hours. [16] [20]
The United States Food and Drugs Administration is warning pet owners about a common medication given to pets to treat arthritis. The F.D.A. now says that the drug Librela may be associated with ...
These adverse effects are more likely during rapid changes between antipsychotic agents, so making a gradual change between antipsychotics minimises these withdrawal effects. [159] The British National Formulary recommends a gradual dose reduction when discontinuing antipsychotic treatment to avoid acute withdrawal symptoms or rapid relapse ...
It has weak antipsychotic effects but is generally not used to treat psychoses. [3] It acts similar to chlorpromazine and causes sedation. [3] It has predominantly anticholinergic side effects, though extrapyramidal side effects are not uncommon. It belongs to the typical antipsychotic and phenothiazine class of drugs. [5]
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Serious side effects may include movement disorders including tardive dyskinesia and neuroleptic malignant syndrome. [6] Use in pregnancy and breastfeeding is generally not recommended. [ 10 ] It is a typical antipsychotic which is believed to work by reducing the action of dopamine in the brain.
Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.
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