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  2. Lymphoblast - Wikipedia

    en.wikipedia.org/wiki/Lymphoblast

    The Chronic Lymphocytic Leukemia Research Consortium defines a lymphoblast as "A lymphocyte that has become larger after being stimulated by an antigen. Lymphoblasts look like immature lymphocytes, and were once thought to be precursor cells." [4] Commonly, when speaking about leukemia, "blast" is used as an abbreviation for lymphoblasts.

  3. Reactive lymphocyte - Wikipedia

    en.wikipedia.org/wiki/Reactive_lymphocyte

    Reactive lymphocyte surrounded by red blood cells. In immunology, reactive lymphocytes, variant lymphocytes, atypical lymphocytes, Downey cells or Türk cells are cytotoxic (CD8 +) lymphocytes that become large as a result of antigen stimulation. Typically, they can be more than 30 μm in diameter with varying size and shape.

  4. White blood cell differential - Wikipedia

    en.wikipedia.org/wiki/White_blood_cell_differential

    A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...

  5. Lymphocyte - Wikipedia

    en.wikipedia.org/wiki/Lymphocyte

    A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...

  6. Centroblast - Wikipedia

    en.wikipedia.org/wiki/Centroblast

    B cells begin expressing CD27 at the beginning of the centroblast stage and lose the cell marker after differentiating into centrocytes. CD27 is an important marker for germinal center formation in the lymphoid follicle and is produced by centroblasts interacting with CD28+ helper T cells.

  7. Nuclear–cytoplasmic ratio - Wikipedia

    en.wikipedia.org/wiki/Nuclear–cytoplasmic_ratio

    For example, "blast" forms of erythrocytes, leukocytes, and megakaryocytes start with an N:C ratio of 4:1, which decreases as they mature to 2:1 or even 1:1 (with exceptions for mature thrombocytes and erythrocytes, which are anuclear cells, and mature lymphocytes, which only decrease to a 3:1 ratio and often retain the original 4:1 ratio). [1]

  8. Acute lymphoblastic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_lymphoblastic_leukemia

    Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [1]

  9. Immunoblast - Wikipedia

    en.wikipedia.org/wiki/Immunoblast

    The majority of lymphocytes are small and have a thin rim of cytoplasm, 6–9 μm in diameter, about the same size as erythrocytes (diameter 7.5 μm). Large lymphocytes (12–18 μm in diameter) are probably activated, i.e. immunoblasts, cells with a paler and wider rim of cytoplasm and are often mistaken for monocytes.

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