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The condition is also referred to as "cervical dystonia". Both agonist and antagonist muscles contract simultaneously during dystonic movement. [1] Causes of the disorder are predominantly idiopathic. A small number of patients develop the disorder as a result of another disorder or disease. Most patients first experience symptoms midlife.
Blepharospasm may be associated with dystonia in other parts of the body, particularly Meige's Syndrome. [27] [28] [4] Blepharospasm may be associated with Parkinson's Disease, but the causal mechanism is still not clear. [29] [30] In rare cases, blepharospasm is associated with multiple sclerosis. [31] [32]
Rapid-onset dystonia parkinsonism and alternating hemiplegia of childhood: DYT13 607671: unknown, near D1S2667 [8] 1p36.32-p36.13 Autosomal dominant cranio-cervical/upper limb dystonia in one Italian family DYT14 See DYT5 DYT15 607488: unknown 18p11 [9] Myoclonic dystonia not linked to SGCE mutations DYT16 612067: PRKRA: 2q31.3
DBS is effective in treating primary generalized dystonia, and also used for focal dystonias such as cervical dystonia and task-specific dystonias (e.g., writer's cramp). In dystonia, marked effects can be reached by targeting the GPi using high frequency DBS, with large randomized trials demonstrating improvements of ~45% and significant ...
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Meige's is commonly misdiagnosed and most doctors will not be familiar with this condition due to its rare incidence. Usually, a neurologist specializing in psychomotor disorders can detect Meige's. There are currently no technological diagnostic tools to detect Meige's, as it cannot be identified using blood chemistry analysis or radiological ...
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