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The Age-Related Eye Disease Study (AREDS) was a clinical trial sponsored by the National Eye Institute that ran from 1992 to 2001. [1] The study was designed to: investigate the natural history and risk factors of age-related macular degeneration (AMD) and cataracts, and
Dietary supplements may be suggested for people with AMD, with the goal of reducing damage to the cells in the retina with antioxidants. The formulations commonly suggested are known as AREDS . The specific vitamins and minerals in AREDS-1 are vitamin C (500 mg), zinc (80 mg), vitamin E (400 IU), copper (2 mg) and beta-carotene (15 mg).
The AREDS2 preparation contained only two of the macular pigment’s three carotenoids (lutein and 3R,3´R-zeaxanthin), and did not include meso-zeaxanthin, which is the dominant carotenoid at the centre of the macula, the presence of which is essential for maximum collective antioxidant effect. [13]
Age-Related Eye Disease Study 2 (AREDS2): This study investigated the roles of zinc and beta-carotene in the original AREDS formulation. It also examined whether adding omega-3 fatty acids and the antioxidants lutein and zeaxanthin would improve the effectiveness of the AREDS formulation.
Looking for vitamin deficiencies. Stimulating your senses. Protecting your head from injuries. Turning off screens a few hours before bed. You Might Also Like. Can Apple Cider Vinegar Lead to ...
Zeaxanthin supplements are typically taken on the supposition of supporting eye health. Although there are no reported side effects from taking zeaxanthin supplements, the actual health effects of zeaxanthin and lutein are not proven, [ 5 ] [ 6 ] [ 7 ] and, as of 2018, there is no regulatory approval in the European Union or the United States ...
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