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  2. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    In people with heart failure, NSAIDs increase mortality risk (hazard ratio) by approximately 1.2–1.3 for naproxen and ibuprofen, 1.7 for rofecoxib and celecoxib, and 2.1 for diclofenac. [68] On 9 July 2015, the Food and Drug Administration (FDA) toughened warnings of increased heart attack and stroke risk associated with nonsteroidal anti ...

  3. Ibuprofen - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen

    Long-term use has been associated with kidney failure, and rarely liver failure, and it can exacerbate the condition of patients with heart failure. [8] At low doses, it does not appear to increase the risk of heart attack; however, at higher doses it may. [10] Ibuprofen can also worsen asthma. [10]

  4. Transdermal analgesic patch - Wikipedia

    en.wikipedia.org/wiki/Transdermal_analgesic_patch

    Nitroglycerin, also known as glyceryl trinitrate (GTN), a medication used for heart failure, high blood pressure, anal fissures, painful periods, and to treat and prevent chest pain, can also be found in patches. Beyond these are patches that contain drugs such as diclofenac and lidocaine and various other drugs.

  5. Mefenamic acid - Wikipedia

    en.wikipedia.org/wiki/Mefenamic_acid

    Mefenamic acid is contraindicated in people who have shown hypersensitivity reactions such as urticaria and asthma to this drug or to other NSAIDs (e.g. aspirin); those with peptic ulcers or chronic inflammation of the gastrointestinal tract; those with kidney or liver disease; heart failure; after coronary artery bypass surgery; and during the third trimester of pregnancy.

  6. Prostaglandin inhibitors - Wikipedia

    en.wikipedia.org/wiki/Prostaglandin_inhibitors

    Prostaglandin inhibitors are drugs that inhibit the synthesis of prostaglandin in human body. [1] There are various types of prostaglandins responsible for different physiological reactions such as maintaining the blood flow in stomach and kidney, regulating the contraction of involuntary muscles and blood vessels, and act as a mediator of inflammation and pain.

  7. FDA warning suggests painkillers may trigger heart attacks ...

    www.aol.com/news/2015-07-22-fda-warning-suggests...

    NEW YORK, New York (Pix 11) -- A new FDA warning says some painkillers may trigger heart attacks or strokes, even in people who don't have existing heart conditions. It's always been known that ...

  8. Metamizole - Wikipedia

    en.wikipedia.org/wiki/Metamizole

    Metamizole or dipyrone is a painkiller, spasm reliever, and fever reliever drug. It is most commonly given by mouth or by intravenous infusion. [13] [11] [14] It belongs to the ampyrone sulfonate family of medicines and was patented in 1922. Metamizole is marketed under various trade names.

  9. Management of heart failure - Wikipedia

    en.wikipedia.org/wiki/Management_of_heart_failure

    Sleep apnea is an under-recognized risk factor for heart failure. Uncontrolled sleep apnea may increase the risk of heart failure by up to 140%. [4] Weight reduction – through physical activity and dietary modification, as obesity is a risk factor for heart failure and left ventricular hypertrophy. Effective weight management has been shown ...

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