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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban, sold under the brand name Eliquis, ... Mechanism of action. Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and ...

  3. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The second one was apixaban (Eliquis), approved in Europe in 2011 [2] and in the United States in 2012. [3] The third one edoxaban (Lixiana, Savaysa) was approved in Japan in 2011 and in Europe and the US in 2015. [4] Betrixaban (Bevyxxa) was approved in the US in 2017.

  4. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    They have a rapid onset and offset of action. This means it is often possible to pause them 12 to 48 hours before surgery and resume them shortly after the surgery. By contrast, warfarin and phenprocoumon are often paused up to a week before surgery, and low-molecular-weight heparins are used to "bridge" the therapy gap, typically for several ...

  5. ELIQUIS® (apixaban) Demonstrates Consistent Reductions in ...

    www.aol.com/news/2012-10-01-eliquis-apixaban...

    ELIQUIS ® (apixaban) Demonstrates Consistent Reductions in Stroke and Systemic Embolism, Major Bleeding and Mortality Compared to Warfarin in Patients with Nonvalvular Atrial Fibrillation at ...

  6. ACE inhibitor - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor

    Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. [1] [2] This class of medicine works by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.

  7. FDA Clears Anticlotting Drug Eliquis - AOL

    www.aol.com/news/2012-12-28-fda-clears-anti...

    The Food and Drug Administration has granted approval for the next-generation anticlotting medication Eliquis, the regulator announced in a news release. The drug, administered in the form of a ...

  8. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

  9. I Found a New Method for Scrambling Eggs and It's the Only ...

    www.aol.com/found-method-scrambling-eggs-only...

    The Perfect Scrambled Egg Method. I don't stray from my tried-and-true ratio, but have introduced two big changes: First, the splash of cream is replaced by a small splash of good olive oil.

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