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Long-term use of benzodiazepines can induce perceptual disturbances and depersonalization in some people, even in those taking a stable daily dosage, and it can also become a protracted withdrawal feature of the benzodiazepine withdrawal syndrome. [54] In addition, chronic use of benzodiazepines is a risk factor for blepharospasm. [55]
The effectiveness of clonazepam in the short-term treatment of panic disorder has been demonstrated in controlled clinical trials. Some long-term trials have suggested a benefit of clonazepam for up to three years without the development of tolerance. [33] Clonazepam is also effective in the management of acute mania. [34]
A number of studies have drawn an association between long-term benzodiazepine use and neuro-degenerative disease, particularly Alzheimer's disease. [150] It has been determined that long-term use of benzodiazepines is associated with increased dementia risk, even after controlling for protopathic bias. [13]
Anxiety medications called benzodiazepines like alprazolam (Xanax®), diazepam (Valium®), and clonazepam (Klonopin®) can be used to quickly reduce anxiety attack symptoms.
Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule.
Clonazepam. Better known as Klonopin, this medication is sometimes prescribed for anxiety disorders like panic disorder, as well as for seizures. Clorazepate. Sold under the brand names Tranxene ...
The long-term effects of benzodiazepines are still not fully understood. Long-term benzodiazepine use is associated with attentional and visuospatial functional impairments. Withdrawal from benzodiazepines can lead to improved alertness and decreased forgetfulness in the elderly. Withdrawal led to statistically significant improvements in ...
Is Ozempic Safe to Take Long-Term? Ozempic (semaglutide) is approved by the U.S. Food and Drug Administration (FDA) for managing blood sugar levels in type 2 diabetes patients.