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The bioavailability of levmetamfetamine is approximately 100%. [2] [3] The peak levels of levmetamfetamine range from 3.3 to 31.4 ng/mL with single oral doses of 1 to 10 mg and from 65.4 to 125.9 ng/mL with single intravenous doses of 0.25 to 0.5 mg/kg.
Rhinitis medicamentosa (or RM, also known as rebound congestion) is a condition of rebound nasal congestion suspected to be brought on by extended use of topical decongestants (e.g., oxymetazoline, phenylephrine, xylometazoline, and naphazoline nasal sprays) and certain oral medications (e.g., sympathomimetic amines and various 2-imidazolines) that constrict blood vessels in the lining of the ...
Many mass-marketed inhaler and nasal spray formulations contain benzalkonium chloride as a ... A 2014 case study detailing the fatal ingestion of up to 8.1 oz (240 ml ...
Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum. A recent clinical trial has shown that a corticosteroid nasal spray may be useful in reversing this condition. [3] Topical nasal decongestants include: Oxymetazoline; Phenylephrine; Xylometazoline
In 1952, Vicks began selling cough syrup, and in 1959 they introduced Sinex Nasal Spray. [7] The company began selling NyQuil in 1966. [ 7 ] The parent company became Richardson-Merrell and then in 1982 divided into prescription drug company Merrell Dow (sold to Dow Chemical Company ) and over-the-counter drug company Richardson-Vicks which ...
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