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A single 15 mg dose of mirtazapine to healthy volunteers has been found to result in over 80% occupancy of the H 1 receptor and to induce intense sleepiness. [92] After a short period of chronic treatment, however, the H 1 receptor tends to sensitize and the antihistamine effects become more tolerable. Many patients may also dose at night to ...
The U.S. Veterans Affairs and Department of Defense 2015 guidelines on substance use disorders list topiramate as a "strong for" in its recommendations for alcohol use disorder. [ 30 ] Other uses include treatment of obesity, [ 31 ] [ 32 ] binge eating disorder , [ 33 ] and off-setting weight gain induced by taking antipsychotic medications.
Fasudil is a potent Rho-kinase inhibitor and vasodilator. [1] Since it was discovered, it has been used for the treatment of cerebral vasospasm, which is often due to subarachnoid hemorrhage, [2] as well as to improve the cognitive decline seen in stroke patients.
Note: "Notable" is to mean side-effects that are particularly unique to the antipsychotic drug in question. For example, clozapine is notorious for its ability to cause agranulocytosis. If data on the propensity of a particular drug to cause a particular AE is unavailable an estimation is substituted based on the pharmacologic profile of the drug.
Tardive dyskinesia (TD) is an iatrogenic disorder that results in involuntary repetitive body movements, which may include grimacing, sticking out the tongue or smacking the lips, [1] which occurs following treatment with medication. [6] [7] Additional motor symptoms include chorea or athetosis. [1]
Haloperidol, sold under the brand name Haldol among others, is a typical antipsychotic medication. [9] Haloperidol is used in the treatment of schizophrenia, tics in Tourette syndrome, mania in bipolar disorder, delirium, agitation, acute psychosis, and hallucinations from alcohol withdrawal.
Some drugs are inactive in the digestive tract, but this can be avoided if held between the upper lip and gum. This prevents the substances from getting swallowed with salivation , as would normally occur between the lower lip and gum, permitting slow release of the drug to prolong the duration of action.
Hydrocortisone is a corticosteroid that is clinically used to relieve the pain and discomfort of mouth ulcers and functions to speed the healing of mouth ulcers. [citation needed] Common side effects include: oral thrush, visual disturbances (e.g. blurry vision), worsening of diabetes, worsening of mouth infections, and allergic reactions (e.g. skin rash).