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Ibuprofen is a weaker anti-inflammatory agent than other NSAIDs. [10] Ibuprofen was discovered in 1961 by Stewart Adams and John Nicholson [12] while working at Boots UK Limited and initially marketed as Brufen. [13] It is available under a number of brand names including Advil, Motrin, and Nurofen.
An enteric coating is a polymer barrier applied to oral medication that prevents its dissolution or disintegration in the gastric environment. [1] This helps by either protecting drugs from the acidity of the stomach, the stomach from the detrimental effects of the drug, or to release the drug after the stomach (usually in the upper tract of the intestine). [2]
Absorption is the journey of a drug travelling from the site of administration to the site of action. [1] [2]The drug travels by some route of administration (oral, topical-dermal, etc.) in a chosen dosage form (e.g., tablets, capsules, or in solution). [3]
Tablets to swallow, chew or dissolve in water or under the tongue; Capsules and chewable capsules (with a coating that dissolves in the stomach or bowel to release the medication there) Time-release or sustained-release tablets and capsules (which release the medication gradually) Powders or granules; and oral liquid dosage forms: [5] Teas; Drops
Buccal tablets offer many advantages over other solid dosage forms also intended for oral administration (e.g. enteric-coated tablets, chewable tablets, and capsules). Buccal tablets can be considered in patients who experience difficulty in swallowing, since these tablets are absorbed into the blood stream between the gum and cheek.
A tablet can be formulated to deliver an accurate dosage to a specific site in the body; it is usually taken orally, but can be administered sublingually, buccally, rectally or intravaginally. The tablet is just one of the many forms that an oral drug can take such as syrups, elixirs, suspensions, and emulsions.
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