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The two different kinds of melasma are epidermal and dermal. Epidermal melasma results from melanin pigment that is elevated in the suprabasal layers of the epidermis. [citation needed] Dermal melasma occurs when the dermal macrophages have an elevated melanin level. [6] Melasma is usually diagnosed visually or with assistance of a Wood's lamp ...
The epidermis is the most superficial layer of skin, a squamous epithelium with several strata: the stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, and stratum basale. [8] Nourishment is provided to these layers by diffusion from the dermis since the epidermis is without direct blood supply.
That's because "many patients with melasma have a component of dermal melasma, rather than purely epidermal, meaning that the pigment sits in deeper layers of the skin in addition to superficial ...
In short, melasma is a chronic skin condition that appears as darkened areas on the face due to an overproduction of melanin, says Gina Charles, MO, a family physician specializing in skincare. It ...
H&E stained section of human skin. The dermoepidermal junction or dermal-epidermal junction (DEJ) is the interface between the epidermal and the dermal layers of the skin. The basal cells of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which ...
What is melasma? “Melasma is a skin condition marked by a darkening of the skin, specifically of the face,” says Amy Wechsler, MD, FAAD, a New York City-based, double board-certified ...
Induration is dermal thickening causing the cutaneous surface to feel thicker and firmer. [29] Atrophy refers to a loss of skin, and can be epidermal, dermal, or subcutaneous. [30] With epidermal atrophy, the skin appears thin, translucent, and wrinkled. [29] Dermal or subcutaneous atrophy is represented by depression of the skin. [29]
There are a wide range of depigmenting treatments used for hyperpigmentation conditions, and responses to most are variable. [11]Most often treatment of hyperpigmentation caused by melanin overproduction (such as melasma, acne scarring, liver spots) includes the use of topical depigmenting agents, which vary in their efficacy and safety, as well as in prescription rules.
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