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Sankalp India Foundation has been offering bone marrow transplantation for patients suffering from thalassemia. The organisation started the first bone marrow transplantation center In collaboration with People Tree Hospitals and Cure2Children Foundation, Italy in Bangalore in August 2015. [12]
Thalassemia prevalence in India is 3-4%, with 10,000 to 12,000 reported thalassemia births taking place every year. It is also estimated that there are 30 million thalassemia carriers in the country. With NAT tested blood, these patients live longer and maintain their quality of life.
DATRI (meaning 'donor' in Sanskrit) [1] is a not-for-profit organization registered in 2009 as a Section 8 company under Government of India. [2] DATRI is one of the largest unrelated blood stem cell donors registry in India, [3] that helps patients with blood cancer and other fatal blood disorders to find a HLA (Human Leukocyte Antigen) matched Blood Stem Cell donor. [4]
The hospital provides an in-patient unit for people suffering from Thalassemia. Though this is a 100-bed facility, it can easily accommodate 30-40 patients (for blood transfusion) suffering from this ailment. [1] This is an initiative to benefit patients so that unused space in the hospital can be utilized for a good purpose.
β thalassemia intermedia is caused by a β + /β o or β + /β + genotype. In this form, some hemoglobin A is produced; β thalassemia minor is caused by a β/β o or β/β + genotype. Only one of the two β globin alleles contains a mutation, so β chain production is not terribly compromised and patients may be relatively asymptomatic.
Beta-thalassemia; Other names: Microcytemia, beta type [1] Beta thalassemia genetics, the picture shows one example of how beta thalassemia is inherited. The beta globin gene is located on chromosome 11. A child inherits two beta globin genes (one from each parent). Specialty: Hematology: Types: Thalassemia minor, intermediate and major [2] Causes
The idea behind establishing such an entity came about when President of the foundation met few kidney and thalassemia patients in 1991. [1] Their inappropriate living and medical condition forced her to travel to provinces to collect first hand information and get herself more familiarized with patients.
Thalassemia patients may also be faced with potential oxidative damage to brain cells as the brain has high oxygen demands, but contains relatively low levels of antioxidant agents for protection against oxidation. The presence of excess iron in the brain may lead to higher concentrations of free radicals.