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  2. Pembrolizumab - Wikipedia

    en.wikipedia.org/wiki/Pembrolizumab

    In July 2015, pembrolizumab received marketing approval in the European Union. [19] [61] [13] In October 2015, the US FDA approved pembrolizumab for the treatment of metastatic non-small cell lung cancer (NSCLC) in people whose tumors express PD-L1 and who have failed treatment with other chemotherapeutic agents. [62] [63] [64]

  3. PD-1 and PD-L1 inhibitors - Wikipedia

    en.wikipedia.org/wiki/PD-1_and_PD-L1_inhibitors

    Pembrolizumab (Keytruda, formerly MK-3475 and lambrolizumab) was developed by Merck and first approved by the Food and Drug Administration in 2014 for the treatment of melanoma. It was later approved for metastatic non-small cell lung cancer and head and neck squamous cell carcinoma .

  4. Tissue-agnostic cancer drug - Wikipedia

    en.wikipedia.org/wiki/Tissue-agnostic_cancer_drug

    Tissue-agnostic cancer drugs are antineoplastic drugs that treat cancers based on the mutations that they display, instead of the tissue type in which they appear. [1] [2] [3] Tissue-agnostic drugs that have been approved for medical use include Pembrolizumab, Larotrectinib, Selpercatinib, Entrectinib, and Pralsetinib.

  5. Merck's Keytruda Secures First FDA-Approval For Rare Form ...

    www.aol.com/mercks-keytruda-secures-first-fda...

    Wednesday, the FDA approved Merck & Co Inc’s (NYSE:MRK) Keytruda (pembrolizumab) in combination with pemetrexed and platinum chemotherapy for the first-line treatment of adult patients with ...

  6. Merck's Experimental Favezelimab/Keytruda Combo Fails ... - AOL

    www.aol.com/mercks-experimental-favezelimab...

    Concurrently, on Wednesday, Japan’s drug regulator approved new indications for Keytruda (pembrolizumab), in certain lung and urothelial cancers. Merck Stock Prediction For 2024

  7. Checkpoint inhibitor - Wikipedia

    en.wikipedia.org/wiki/Checkpoint_inhibitor

    It was approved in 2014. Nivolumab is approved to treat melanoma, lung cancer, kidney cancer, bladder cancer, head and neck cancer, and Hodgkin's lymphoma. [16] Pembrolizumab (brand name Keytruda) is another PD-1 inhibitor that was approved by the FDA in 2014 and was the second checkpoint inhibitor approved in the United States. [17]

  8. 19 drug approvals in 2024 that had 'big clinical impact ... - AOL

    www.aol.com/19-drug-approvals-2024-had-093022917...

    GoodRx released a list of 19 of the most influential drugs and vaccines approved by the FDA in 2024 to treat a variety of conditions. These medications are “slated to make a big clinical impact."

  9. Favezelimab/pembrolizumab - Wikipedia

    en.wikipedia.org/wiki/Favezelimab/pembrolizumab

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