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In other words, as many as 4 million people in the U.S. who currently take statins for primary prevention — meaning they have not had a cardiovascular event such as a stroke or heart attack ...
New research finds that many people currently taking statins to lower cholesterol may not actually need this medication. An analysis, published in JAMA Internal Medicine , investigates how statin ...
Statins are a medication type that can help people at risk for atherosclerotic cardiovascular disease. Doctors look at several factors to determine if statin therapy makes the most sense for ...
The gene SLCO1B1 (Solute carrier organic anion transporter family member 1B1) codes for an organic anion-transporting polypeptide that is involved in the regulation of the absorption of statins. A common variation in this gene was found in 2008 to significantly increase the risk of myopathy.
The effects of rosuvastatin on low-density lipoprotein (LDL) cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.
10599 28253 Ensembl ENSG00000134538 ENSMUSG00000030236 UniProt Q9Y6L6 Q9JJL3 RefSeq (mRNA) NM_006446 NM_020495 NM_178235 RefSeq (protein) NP_006437 NP_065241 Location (UCSC) Chr 12: 21.13 – 21.24 Mb Chr 6: 141.58 – 141.63 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Solute carrier organic anion transporter family member 1B1 is a protein that in humans is encoded by the SLCO1B1 ...
Statins appear to be effective at preventing cardiovascular disease and death in older adults, according to new research. Most clinical trials evaluating statins have not included people 75 and ...
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