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Research on the genome also raises the possibility of genetically engineering silkworms to produce proteins, including pharmacological drugs, in the place of silk proteins. Bombyx mori females are also one of the few organisms with homologous chromosomes held together only by the synaptonemal complex (and not crossovers) during meiosis. [14]
Bombyx mori bidensovirus Bidensovirus is a genus of single stranded DNA viruses that infect invertebrates. The species in this genus were originally classified in the family Parvoviridae (subfamily Densovirinae ) but were moved to a new genus because of significant differences in the genomes.
The best-known species is Bombyx mori , or domestic silk moth, native to northern China and domesticated for millennia. Another well-known species is Bombyx mandarina , also native to Asia. Taxonomy
The linear genome is between of 6–7.5 kilobases in length [1] and encodes one large open reading frame. It is capped at the 5’ terminus. The 3’ terminus may have a tRNA-like structure or a polyA tract, depending upon the species. The genome is relatively cytosine rich. [citation needed]
The human genome contains an estimated 100,000 truncated and 4,000 full-length LINE-1 elements. [10] Due to the accumulation of random mutations, the sequence of many LINEs has degenerated to the extent that they are no longer transcribed or translated. Comparisons of LINE DNA sequences can be used to date transposon insertions in the genome.
Ld130, also known as baculovirus F-protein from Lymantria dispar (LdMNPV) is suggested to be an ancestral envelope fusion protein which has been replaced by non-orthologous gene replacement with gp64 in AcMNPV, Bombyx mori (BmNPV) and Orgyia pseudotsugata (OpMNPV) while they still retain the ld130 gene. [citation needed]
The first PGRP was discovered in 1996 by Masaaki Ashida and coworkers, who purified a 19 kDa protein present in the hemolymph and cuticle of a silkworm (Bombyx mori), and named it Peptidoglycan Recognition Protein, because it specifically bound peptidoglycan and activated the prophenoloxidase cascade. [5]
The cabbage looper genome is larger than the Drosophila melanogaster genome (180Mb) but smaller than the Bombyx mori genome (530mb). [ 48 ] [ 49 ] It encodes at least 108 cytochrome P450 enzymes, 34 glutathione S-transferases , 87 carboxylesterases , and 54 ATP-binding cassette transporters , some of which may be involved in its insecticide ...