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Goodpasture syndrome (GPS), also known as anti–glomerular basement membrane disease, is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs, glomerulonephritis, [1] and kidney failure. [2]
Ernest William Goodpasture (October 17, 1886 – September 20, 1960) was an American pathologist and physician. Goodpasture advanced the scientific understanding of the pathogenesis of infectious diseases, parasitism, and a variety of rickettsial and viral infections.
Anti-glomerular basement membrane antibody (anti-GBM Ab) is an antibody which is found in Goodpasture's syndrome but not found in microscopic polyangiitis.. Some sources consider "anti-GBM disease" and "Goodpasture disease" to be synonymous terms describing histological presentation, reserving the term "Goodpasture syndrome" for clinical presentation.
Goodpasture syndrome: Kidneys, lungs: Anti-GBM antibodies Confirmed 1 per million people [46] IgA nephropathy: Kidneys: IgA autoantibodies Confirmed 3.5 per 100,000 [47] Membranous nephropathy: Kidneys: Anti-PLA2R antibodies Confirmed 10 per 100,000 [48] Lupus nephritis: Kidneys: Anti-dsDNA, Anti-Sm, Anti-nuclear antibodies Confirmed Up to 60% ...
Goodpasture syndrome; Gordon syndrome; Gougerot–Blum syndrome; Gourmand syndrome; Gouverneur's syndrome; GRACILE syndrome; Graham-Little syndrome; Gray baby syndrome; Gray platelet syndrome; Greater trochanteric pain syndrome; Green nail syndrome; Greig cephalopolysyndactyly syndrome; Grinspan's syndrome; Griscelli syndrome type 2; Griscelli ...
Pulmonary-renal syndrome (PRS) is a rare medical syndrome in which respiratory failure involving bleeding in the lungs and kidney failure (glomerulonephritis) occur. [1] PRS is associated with a high rate of morbidity and death. [1] The term was first used by Goodpasture in 1919 to describe the association of respiratory and kidney failure. [1]
He was diagnosed with Goodpasture syndrome, a rare autoimmune disorder that affects the kidneys and lungs. [9] Merritt was struggling with his health and finances, so his manager Wal Bishop and Australian music industry friends, organised a Concert for Max benefit held at the Palais Theatre, St Kilda, Victoria, on 21 October 2007 which raised ...
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