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  2. Comparison of bicalutamide with other antiandrogens

    en.wikipedia.org/wiki/Comparison_of_bicalutamide...

    Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...

  3. List of 5α-reductase inhibitors - Wikipedia

    en.wikipedia.org/wiki/List_of_5α-reductase...

    This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...

  4. 5α-Reductase inhibitor - Wikipedia

    en.wikipedia.org/wiki/5α-reductase_inhibitor

    Thus, inhibition results in decreased amounts of DHT. Because of this, slight elevations in testosterone and estradiol levels occur. [36] The 5α-reductase reaction is a rate-limiting step in the testosterone reduction and involves the binding of NADPH to the enzyme followed by the substrate. [4] [37] Substrate + NADPH + H + → 5α-substrate ...

  5. What You Need to Know Before You Take Testosterone - AOL

    www.aol.com/lifestyle/know-testosterone...

    To be sure, get a fasting testosterone test at your doctors, preferably in the morning, when the hormone’s levels peak. Repeat the test at least once, with the second a day or more after the first.

  6. List of androgens/anabolic steroids (alternate) - Wikipedia

    en.wikipedia.org/wiki/List_of_androgens/anabolic...

    This is a list of androgens/anabolic steroids (AAS) or testosterone derivatives. Esters are mostly not included in this list; for esters, see here instead. The major classes of testosterone derivatives include the following (as well as combinations thereof): Testosterone derivatives: immediate derivatives of testosterone not falling into the ...

  7. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Androgen receptor antagonistic potency of spironolactone, cyproterone acetate, and flutamide in castrated male rats treated with exogenous testosterone (as measured by inhibition of androgen-dependent ventral prostate weight). [27] Spironolactone is an antagonist of the AR, the biological target of androgens like testosterone and DHT.

  8. How Saw Palmetto Might Help Your Prostate - AOL

    www.aol.com/lifestyle/saw-palmetto-might-help...

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  9. 5α-Reductase - Wikipedia

    en.wikipedia.org/wiki/5α-Reductase

    Additionally, it has been claimed that alfatradiol works through this mechanism of activity (5α-reductase), as well as the Ganoderic acids in lingzhi mushroom, and the Saw Palmetto. Inhibition of 5α-reductase results in decreased conversion of testosterone to DHT, leading to increased testosterone and estradiol.

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