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  2. Factor X - Wikipedia

    en.wikipedia.org/wiki/Factor_X

    There are two commercially available Factor X concentrates: "Factor X P Behring" manufactured by CSL Behring, [10] and high purity Factor X Coagadex produced by Bio Products Laboratory and approved for use in the United States by the FDA in October 2015, and in the EU in March 2016, after earlier acceptance by CHMP and COMP. [11] [12] [13] [14]

  3. X Development - Wikipedia

    en.wikipedia.org/wiki/X_Development

    X Development LLC, [2] [3] [4] doing business as X (formerly Google X), [1] is an American semi-secret research and development facility and organization founded by Google in January 2010. [ 5 ] [ 6 ] X has its headquarters about a mile and a half from Alphabet's corporate headquarters, the Googleplex , in Mountain View, California .

  4. Mixing study - Wikipedia

    en.wikipedia.org/wiki/Mixing_study

    Fresh normal plasma has all the blood coagulation factors with normal levels. If the problem is a simple factor deficiency, mixing the patient plasma 1:1 with plasma that contains 100% of the normal factor level results in a level ≥50% in the mixture (say the patient has an activity of 0%; the average of 100% + 0% = 50%). [3]

  5. Factor X deficiency - Wikipedia

    en.wikipedia.org/wiki/Factor_X_deficiency

    Factor X deficiency (X as Roman numeral ten) is a bleeding disorder characterized by a lack in the production of factor X (FX), an enzyme protein that causes blood to clot in the coagulation cascade. Produced in the liver FX when activated cleaves prothrombin to generate thrombin in the intrinsic pathway of coagulation.

  6. Prothrombinase - Wikipedia

    en.wikipedia.org/wiki/Prothrombinase

    Both factor X and factor V circulate in the blood as inactive precursors prior to activation by the coagulation cascade. The inactive zymogen factor X consists of two chains, a light chain (136 residues) and a heavy chain (306 residues).

  7. Antithrombin III deficiency - Wikipedia

    en.wikipedia.org/wiki/Antithrombin_III_deficiency

    Antithrombin III deficiency (abbreviated ATIII deficiency) is a deficiency of antithrombin III.This deficiency may be inherited or acquired. [1] It is a rare hereditary disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism, and repetitive intrauterine fetal death (IUFD). [2]

  8. Dilute Russell's viper venom time - Wikipedia

    en.wikipedia.org/wiki/Dilute_Russell's_viper...

    Russell's viper, Daboia russelii Dilute Russell's viper venom time (dRVVT) is a laboratory test often used for detection of lupus anticoagulant (LA). It is an assessment of the time for blood to clot in the presence of a diluted amount of venom from Russell's viper (Daboia russelii), a highly venomous snake native to the Indian subcontinent and named after the herpetologist Patrick Russell.

  9. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Direct factor Xa inhibitors can be considered as an alternative to warfarin, particularly if a person is on several other medications that interact with warfarin, or if attending medical appointments and laboratory monitoring becomes difficult. [8]

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