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  2. Anastrozole - Wikipedia

    en.wikipedia.org/wiki/Anastrozole

    The bioavailability of anastrozole in humans is unknown, but it was found to be well-absorbed in animals. [2] [6] Absorption of anastrozole is linear over a dosage range of 1 to 20 mg/day in humans and does not change with repeated administration. [3] [4] [6] Food does not significantly influence the extent of absorption of anastrozole.

  3. Non steroidal aromatase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Non_steroidal_aromatase...

    Anastrozole is administered orally and has a standard daily dose of 1 mg. Anastrozole has good oral bioavailability and is rapidly absorbed. It takes 2–3 hours for the drug to reach maximum serum concentration. It has been shown that the ingestion of food does not significantly influence the plasma concentration of the drug at a steady-state ...

  4. Aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Aromatase_inhibitor

    Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...

  5. What is Anastrozole? The breast cancer drug that can cut risk ...

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    Women post-menopause with ‘strong family history’ of breast cancer encouraged speak to GP about drug, expert says

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  7. Steroidogenesis inhibitor - Wikipedia

    en.wikipedia.org/wiki/Steroidogenesis_inhibitor

    Anastrozole • Bicalutamide • Dexmedetomidine • Fadrozole • Posaconazole • Ravuconazole: Cholesterol 7α-hydroxylase (CYP7A1) Cholesterol→7α-Hydroxycholesterol (intermediate to bile acids) Ketoconazole • Levoketoconazole: Lanosterol 14α-demethylase (CYP51A1) Lanosterol→4,4-Dimethylcholesta-8(9),14,24-trien-3β-ol (intermediate ...

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  9. Zoledronic acid - Wikipedia

    en.wikipedia.org/wiki/Zoledronic_acid

    An increase in disease-free survival (DFS) was found in the ABCSG-12 trial, in which 1,803 premenopausal women with endocrine-responsive early breast cancer received anastrozole with zoledronic acid. [29] A retrospective analysis of the AZURE trial data revealed a DFS survival advantage, particularly where estrogen had been reduced. [30]

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