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A tophus (Latin: "stone", pl.: tophi) is a deposit of monosodium urate crystals, in people with longstanding high levels of uric acid (urate) in the blood, a condition known as hyperuricemia. Tophi are pathognomonic for the disease gout. Most people with tophi have had previous attacks of acute arthritis, eventually leading to the formation of ...
If you have untreated gout for a long time, something called tophi can develop. Tophi is when uric acid crystals around the joints form larger, hard deposits. It can lead to pain, soft tissue ...
Gout is a disorder of purine metabolism, [5] and occurs when its final metabolite, uric acid, crystallizes in the form of monosodium urate, precipitating and forming deposits (tophi) in joints, on tendons, and in the surrounding tissues. [17]
Gout is a form of inflammatory arthritis characterized by recurrent attacks of a single red, ... It may also result in tophi, kidney stones, or urate nephropathy. [3 ...
How is gout treated and prevented? A doctor can diagnose gout by examining the joints and looking for a pattern of swelling. “We will also look for uric acid crystals either in your joints or ...
Probenecid is primarily used to treat gout and hyperuricemia. Probenecid is sometimes used to increase the concentration of some antibiotics and to protect the kidneys when given with cidofovir . Specifically, a small amount of evidence supports the use of intravenous cefazolin once rather than three times a day when it is combined with probenecid.
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