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The advent of the first low dead space syringe occurred with the creation of 1-ml syringes designed specifically for the administration of insulin. Then amongst the scare of HIV and rising concern of other communicable diseases to healthcare workers the creation of safety syringes occurred in 1988.
The dilution of insulin is such that 1 mL of insulin fluid has 100 standard "units" of insulin. [6] A typical insulin vial may contain 10 mL, for 1000 units. Insulin syringes are made specifically for a patient to inject themselves, and have features to assist this purpose when compared to a syringe for use by a healthcare professional:
Needles in common medical use range from 7 gauge (the largest) to 34 (the smallest). 21-gauge needles are most commonly used for drawing blood for testing purposes, and 16- or 17-gauge needles are most commonly used for blood donation, as the larger luminal cross-sectional area results in lower fluid shear, reducing harm to red blood cells ...
Injector pens remove some of the complications of syringes by allowing the pen to be "pushed" against the skin at a 90-degree angle (removing the need to inject at a proper angle as is the case with syringes), as well as by replacing a long, thin plunger of a syringe with a simple button which is depressed and held to inject the dose.
The Birmingham gauge ranges from 5/0 or 00000, the lowest gauge number corresponding to the largest size of 0.500 inches (12.7 mm), to 36, the highest gauge number corresponding to the smallest size of 0.004 inches (0.10 mm). The increments between gauge sizes are not linear and vary. [2]
The French scale measures the outer diameter of the catheter, not the size of the internal drainage channel (inner diameter). For instance, a two-way catheter of 20 Fr and a three-way catheter of 20 Fr have the same outer diameter, but the three-way catheter has an additional channel for irrigation, reducing the size of its drainage channel.
Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922. [85] [86] This is a chronology of key milestones in the history of the medical use of insulin. For more details on the discovery, extraction, purification, clinical use, and synthesis of insulin, see Insulin
The company was founded in 1897 in New York City by Maxwell Becton and Fairleigh S. Dickinson.It later moved its headquarters to New Jersey. In 2004, BD agreed to pay out US$100 million to settle allegations from competitor Retractable Technologies that it had engaged in anti-competitive behavior to prevent the distribution of Retractable's syringes, which are designed to prevent needlestick ...
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