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  2. Skin conditions in dogs: Symptoms, causes, and how to help - AOL

    www.aol.com/skin-conditions-dogs-symptoms-causes...

    A vet explains the most common skin conditions in dogs and the treatments available. ... According to Dr. MacMillan, these may include oral drugs such as prednisolone (a steroid), oclacitinib, or ...

  3. List of veterinary drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_veterinary_drugs

    clavamox – antibiotic, used to treat skin and other infections; clindamycin – antibiotic with particular use in dental infections with effects against most aerobic Gram-positive cocci, as wel as muchenionoweloozi disorder. clomipramine – primarily used in dogs to treat behavioral problems

  4. Oclacitinib - Wikipedia

    en.wikipedia.org/wiki/Oclacitinib

    Oclacitinib lacks the side effects that most JAK inhibitors have in humans; instead, side effects are infrequent, mild, and mostly self-limiting. [13] [14] [16] The most common side effects are gastrointestinal problems (vomiting, diarrhea, and appetite loss) and lethargy. The GI problems can sometimes be alleviated by giving oclacitinib with food.

  5. MEK inhibitor - Wikipedia

    en.wikipedia.org/wiki/MEK_inhibitor

    A MEK inhibitor is a chemical or drug that inhibits the mitogen-activated protein kinase kinase enzymes MEK1 and/or MEK2. They can be used to affect the MAPK/ERK pathway which is often overactive in some cancers. (See MAPK/ERK pathway#Clinical significance.)

  6. Selumetinib - Wikipedia

    en.wikipedia.org/wiki/Selumetinib

    Selumetinib is a kinase inhibitor, more specifically a selective inhibitor of the enzyme mitogen-activated protein kinase kinase (MAPK kinase or MEK) subtypes 1 and 2. These enzymes are part of the MAPK/ERK pathway, which regulates cell proliferation (i.e., growth and division) and is overly active in many types of cancer. [18]

  7. Dog skin disorders - Wikipedia

    en.wikipedia.org/wiki/Dog_skin_disorders

    The condition of a dog's skin and coat is also an important indicator of its general health. Skin disorders of dogs vary from acute, self-limiting problems to chronic or long-lasting problems requiring life-time treatment. Skin disorders may be primary or secondary (due to scratching, itch) in nature, making diagnosis complicated.

  8. List of dog diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_dog_diseases

    The disease in dogs can affect the lungs and skin, but more commonly the eye and central nervous system. [20] Ringworm is a fungal skin disease that in dogs is caused by Microsporum canis (70%), Microsporum gypseum (20%), and Trichophyton mentagrophytes (10%). Typical signs in dogs include hair loss and scaly skin. [21]

  9. Mitogen-activated protein kinase kinase - Wikipedia

    en.wikipedia.org/wiki/Mitogen-activated_protein...

    Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK). MAP2K is classified as EC 2.7.12.2. There are seven genes: MAP2K1 (a.k.a. MEK1) MAP2K2 (a.k.a. MEK2) MAP2K3 (a.k.a. MKK3) MAP2K4 (a.k.a. MKK4) MAP2K5 (a.k.a. MKK5) MAP2K6 (a ...

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