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The lymph ends its journey in the thoracic duct or right lymphatic duct, which drain into the blood circulation. [10] Several research groups have hypothesized that chronic inflammation is a key regulator in the development of lymphedema. Th cells, particularly Th2 differentiation, play a crucial role in the pathophysiology of lymphedema.
The pathophysiology is not yet well understood. Leukocytoclastic vasculitis is proposed to be the underlying cause resulting in reactive lymphedema. [2] Prolonged standing with full knee extension and minimal movement for a prolonged period of time is postulated to induce a temporary failure in pumping the venous and lymphatic systems in the calf region leading to acute gravity-dependent ...
Lymphotherapy (lymphatic physiotherapy) is a method by which pressure applied on specific lymph nodes alters lymphatic response. Proponents state it can be used for lymphedema [1] and breast cancer. [2]
Lymphedema. Lymphedema is the chronic pooling of lymph fluid in the tissue. Lymphedema can start anywhere in the lymphatic system of the body. It's also a side-effect of some surgical procedures. Kathy Bates is an advocate and supporter for further research for lymphedema. [3] Lymphocytosis. Lymphocytosis is a high lymphocyte count.
Milroy's disease is also known as primary or hereditary lymphedema type 1A or early onset lymphedema. It is a very rare disease with only about 200 cases reported in the medical literature. Milroy's disease is an autosomal dominant condition caused by a mutation in the FLT4 gene which encodes the vascular endothelial growth factor receptor 3 ...
Postinflammatory lymphedema is a condition characterized by swelling of the soft tissues in which an excessive amount of lymph has accumulated, and is caused by repeated bacterial infections. [ 1 ] : 849
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