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  2. Inflammation - Wikipedia

    en.wikipedia.org/wiki/Inflammation

    The term inflammation is not a synonym for infection. Infection describes the interaction between the action of microbial invasion and the reaction of the body's inflammatory response—the two components are considered together in discussion of infection, and the word is used to imply a microbial invasive cause for the observed inflammatory ...

  3. Acute-phase protein - Wikipedia

    en.wikipedia.org/wiki/Acute-phase_protein

    Measurement of acute-phase proteins, especially C-reactive protein, is a useful marker of inflammation in both medical and veterinary clinical pathology. It correlates with the erythrocyte sedimentation rate (ESR), however not always directly.

  4. Procalcitonin - Wikipedia

    en.wikipedia.org/wiki/Procalcitonin

    Immune responses to both organ rejection and severe bacterial infection can lead to similar symptoms such as swelling and fever that can make initial diagnosis difficult. To differentiate between acute rejection of an organ transplant and bacterial infections, plasma procalcitonin levels have been proposed as a potential diagnostic tool. [ 58 ]

  5. Inflammatory cytokine - Wikipedia

    en.wikipedia.org/wiki/Inflammatory_cytokine

    Inflammatory cytokines play a role in initiating the inflammatory response and to regulate the host defence against pathogens mediating the innate immune response. [4] Some inflammatory cytokines have additional roles such as acting as growth factors. [5] Pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α also trigger pathological pain ...

  6. Biomarker (medicine) - Wikipedia

    en.wikipedia.org/wiki/Biomarker_(medicine)

    In medicine, a biomarker is a measurable indicator of the severity or presence of some disease state. It may be defined as a "cellular, biochemical or molecular alteration in cells, tissues or fluids that can be measured and evaluated to indicate normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention."

  7. Cholecystitis - Wikipedia

    en.wikipedia.org/wiki/Cholecystitis

    In someone suspected of having cholecystitis, blood tests are performed for markers of inflammation (e.g. complete blood count, C-reactive protein), as well as bilirubin levels in order to assess for bile duct blockage. [14] Complete blood count typically shows an increased white blood count (12,000–15,000/mcL). [14]

  8. Inflammasome - Wikipedia

    en.wikipedia.org/wiki/Inflammasome

    The inflammasome was discovered by the team of Jürg Tschopp, at the University of Lausanne, in 2002. [17] [18] In 2002, it was first reported by Martinon et al. [17] that NLRP1 (NLR family PYD-containing 1) could assemble and oligomerize into a structure in vitro, which activated the caspase-1 cascade, thereby leading to the production of pro-inflammatory cytokines, including IL-1β and IL-18.

  9. Osteomyelitis - Wikipedia

    en.wikipedia.org/wiki/Osteomyelitis

    Diagnosis is typically suspected based on symptoms and basic laboratory tests as C-reactive protein and erythrocyte sedimentation rate. This is because plain radiographs are unremarkable in the first few days following acute infection. [7] [2] Diagnosis is further confirmed by blood tests, medical imaging, or bone biopsy. [2]