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A combination of two types of therapeutic agents selectively killed breast cancer cells in a clinical trial, offering hope for a new treatment for triple-negative breast cancer.
In the other 20-30%, the breast cancer will return as Stage 4, also known as metastatic, when the cancer has spread to other parts of the body beyond the lymph nodes near the breast ...
In organized studies of new treatments for cancer, the pre-clinical development of drugs, devices, and techniques begins in laboratories, either with isolated cells or in small animals, most commonly rats or mice. In other cases, the proposed treatment for cancer is already in use for some other medical condition, in which case more is known ...
In the United States, trastuzumab emtansine was approved specifically for treatment of HER2-positive metastatic breast cancer (mBC) in patients who have been treated previously with trastuzumab and a taxane (paclitaxel or docetaxel), and who have already been treated for mBC or developed tumor recurrence within six months of adjuvant therapy.
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
The median age at diagnosis is slightly younger for Black women (60) compared to white women (64), and Black women are more likely to die from breast cancer than any other race or ethnic group.
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