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  2. Microtubule - Wikipedia

    en.wikipedia.org/wiki/Microtubule

    The centrosome is critical to mitosis as most microtubules involved in the process originate from the centrosome. The minus ends of each microtubule begin at the centrosome, while the plus ends radiate out in all directions. Thus the centrosome is also important in maintaining the polarity of microtubules during mitosis. [59]

  3. Aster (cell biology) - Wikipedia

    en.wikipedia.org/wiki/Aster_(cell_biology)

    An aster is a cellular structure shaped like a star, consisting of a centrosome and its associated microtubules during the early stages of mitosis in an animal cell. [1]: 221 Asters do not form during mitosis in plants. Astral rays, composed of microtubules, radiate from the centrosphere and look like a cloud. Astral rays are one variant of ...

  4. Spindle apparatus - Wikipedia

    en.wikipedia.org/wiki/Spindle_apparatus

    Micrograph showing condensed chromosomes in blue, kinetochores in pink, and microtubules in green during metaphase of mitosis. In cell biology, the spindle apparatus is the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells.

  5. Mitosis - Wikipedia

    en.wikipedia.org/wiki/Mitosis

    Anaphase during mitosis. During anaphase A, the cohesins that bind sister chromatids together are cleaved, forming two identical daughter chromosomes. [52] Shortening of the kinetochore microtubules pulls the newly formed daughter chromosomes to opposite ends of the cell.

  6. Microtubule organizing center - Wikipedia

    en.wikipedia.org/wiki/Microtubule_organizing_center

    The microtubule-organizing center (MTOC) is a structure found in eukaryotic cells from which microtubules emerge. MTOCs have two main functions: the organization of eukaryotic flagella and cilia and the organization of the mitotic and meiotic spindle apparatus, which separate the chromosomes during cell division.

  7. Centrosome - Wikipedia

    en.wikipedia.org/wiki/Centrosome

    During mitosis, the nuclear membrane breaks down, and the centrosome-nucleated microtubules can interact with the chromosomes to build the mitotic spindle. The mother centriole, the older of the two in the centriole pair, also has a central role in making cilia and flagella .

  8. Mitotic inhibitor - Wikipedia

    en.wikipedia.org/wiki/Mitotic_inhibitor

    Microtubules are created during normal cell functions by assembling (polymerizing) tubulin components, and are disassembled when they are no longer needed. One of the important functions of microtubules is to move and separate chromosomes and other components of the cell for cell division ( mitosis ).

  9. Spindle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Spindle_checkpoint

    During S phase, the centrosome starts to duplicate. Just at the beginning of mitosis, both centrioles achieve their maximal length, recruit additional material and their capacity to nucleate microtubules increases. As mitosis progresses, both centrosomes separate to generate the mitotic spindle. [22]