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Seminiferous tubules are located within the testicles, and are the specific location of meiosis, and the subsequent creation of male gametes, namely spermatozoa.
Testicular seminoma originates in the germinal epithelium of the seminiferous tubules. [4] About half of germ cell tumors of the testicles are seminomas. [5] Treatment usually requires removal of one testicle. However, fertility usually isn't affected. All other sexual functions will remain intact.
The seminal tract is a part of the male reproductive system and consists of seminiferous tubules (tubuli seminiferi recti, rete testis, efferent ducts), epididymides , Vas deferens and ejaculatory ducts.
Sertoli cell-only syndrome (SCOS), also known as germ cell aplasia, is defined by azoospermia where the testicular seminiferous tubules are lined solely with sertoli cells. [2] Sertoli cells contribute to the formation of the blood-testis barrier and aid in sperm generation.
It also has been used as a marker for ovarian cancer. [29] [30] Inhibin B may be used as a marker of spermatogenesis function and male infertility. The mean serum inhibin B level is significantly higher among fertile men (approximately 140 pg/mL) than in infertile men (approximately 80 pg/mL). [31]
Cross-section of a seminiferous tubule of the testis of a rat (250x) The function of Sertoli cells in the Amniota and Anamniota is the same, but they have slightly different properties when compared to each other. Anamnionts (fish and amphibians) employ cystic spermatogenesis in order to produce sperm cells. [22]
In mammals, spermatozoa are produced in the seminiferous tubules and flow into the epididymal duct. The end of the epididymis is connected to the vas deferens. The vas deferens ends with an opening into the ejaculatory duct at a point where the duct of the seminal vesicle also joins the ejaculatory duct. [1]
81930 228421 Ensembl ENSG00000121621 ENSMUSG00000027115 UniProt Q8NI77 Q91WD7 RefSeq (mRNA) NM_031217 NM_139303 RefSeq (protein) NP_112494 NP_647464 Location (UCSC) Chr 11: 28.02 – 28.11 Mb Chr 2: 109.11 – 109.17 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. It is part of the kinesin family of motor ...