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Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [10]
The discovery of antimicrobial agents contributed significantly to UTI management during the 20th century. Nitrofurantoin emerged as the first practical and safe urinary antimicrobial agent, but it was with limited spectrum of activity. [48] Subsequently, in the 1970s, beta-lactam antibiotics and TMP/SMX became available for UTI therapy. [48]
Metronidazole is an antibiotic with an off-label use in eradicating H. pylori for treating gastric ulceration. Resistance of metronidazole is above 15% worldwide. [ 32 ] It is likely to be resistant so is not the first line choice of treatment. [ 44 ]
If azithromycin was prescribed as initial therapy, then give doxycycline 100 mg twice daily for 7 days plus metronidazole 400 – 500 mg twice daily for 5 – 7 days Moxifloxacin 400 mg orally once daily for 7 – 14 days can be given with use of caution, if macrolide-resistant M. genitalium infection is demonstrated [ 9 ]
For men, the signs and symptoms are discharge from the penis, burning or pain when urinating, itching, irritation, or tenderness. In women, the signs and symptoms are discharge from vagina, burning or pain when urinating, anal or oral infections, abdominal pain, or abnormal vaginal bleeding, which may be an indication that the infection has ...
Symptoms from a lower urinary tract infection include suprapubic pain, painful urination , frequency and urgency of urination despite having an empty bladder. [1] Symptoms of a kidney infection, on the other hand, are more systemic and include fever or flank pain usually in addition to the symptoms of a lower UTI. [ 10 ]
Signs and symptoms, when present, may include lower abdominal pain, vaginal discharge, fever, burning with urination, pain with sex, bleeding after sex, or irregular menstruation. [1] Untreated PID can result in long-term complications including infertility , ectopic pregnancy , chronic pelvic pain , and cancer .
In some men, chronic bacterial prostatitis can be severe and highly refractory to treatment or relapsing. [34] [35] In addition, it can be life-threatening due to urinary tract infections (UTIs). [35] Prostatectomy, or prostate removal surgery, has been used rarely and in well-selected patients to treat these kinds of cases.
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