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The original antigenic sin: When the body first encounters an infection it produces effective antibodies against its dominant antigens and thus eliminates the infection. But when it encounters the same infection, at a later evolved stage, with a new dominant antigen, with the original antigen now being recessive, the immune system will still produce the former antibodies against this old "now ...
Original antigenic sin; Vaccine adverse event; Other ways in which antibodies can (unusually) make an infection worse instead of better Blocking antibody, which can be either good or bad, depending on circumstances; Hook effect, most relevant to in vitro tests but known to have some in vivo relevances
This doctrine is known as the original antigenic sin. [21] This phenomenon comes into play particularly in immune responses against influenza , dengue and HIV viruses. [ 25 ] This limitation, however, is not imposed by the phenomenon of polyclonal response, but rather, against it by an immune response that is biased in favor of experienced ...
An illustration that shows how antigens induce the immune system response by interacting with an antibody that matches the molecular structure of an antigen. In immunology, an antigen (Ag) is a molecule, moiety, foreign particulate matter, or an allergen, such as pollen, that can bind to a specific antibody or T-cell receptor. [1]
Original antigenic sin, descriptive diagram. en:Original antigenic sin refers to the propensity of the body's immune system to preferentially utilize immunological memory based on a previous infection when a second slightly different version of that foreign entity is encountered.
Antigen processing and presentation in MHC-I pathway. Cytotoxic T cells (also known as T c, killer T cell, or cytotoxic T-lymphocyte (CTL)) express CD8 co-receptors and are a population of T cells that are specialized for inducing programmed cell death of other cells.
2 Analogy to original sin. 4 comments. 3 Original antigenic sin outdated. 2 comments. 4 Flu vaccination counter-productive ? ... English. Read; Edit; Add topic;
Antigenic drift occurs in both influenza A and influenza B viruses. (Confusion can arise with two very similar terms, antigenic shift and genetic drift. Antigenic shift is a closely related process; it refers to the more dramatic changes in the virus's surface proteins when the genetic material from two or more viruses mix together.