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  2. Functional genomics - Wikipedia

    en.wikipedia.org/wiki/Functional_genomics

    A more focused functional genomics approach might test the function of all variants of one gene and quantify the effects of mutants by using sequencing as a readout of activity. Together these measurement modalities endeavor to quantitate the various biological processes and improve our understanding of gene and protein functions and interactions.

  3. Rapid automatized naming - Wikipedia

    en.wikipedia.org/wiki/Rapid_automatized_naming

    Rapid automatized naming (RAN) is a task that measures how quickly individuals can name aloud objects, pictures, colors, or symbols (letters or digits). Variations in rapid automatized naming time in children provide a strong predictor of their later ability to read, and is independent from other predictors such as phonological awareness, verbal IQ, and existing reading skills. [1]

  4. Sequence analysis - Wikipedia

    en.wikipedia.org/wiki/Sequence_analysis

    Sequence analysis tasks are often non-trivial to resolve and require the use of relatively complex approaches, many of which are the backbone behind many existing sequence analysis tools. Of the many methods used in practice, the most popular include the following: Dynamic programming; Artificial neural network; Hidden Markov model; Support ...

  5. Protein function prediction - Wikipedia

    en.wikipedia.org/wiki/Protein_function_prediction

    For enzymes, predictions of specific functions are especially difficult, as they only need a few key residues in their active site, hence very different sequences can have very similar activities. By contrast, even with sequence identity of 70% or greater, 10% of any pair of enzymes have different substrates; and differences in the actual ...

  6. Critical Assessment of Function Annotation - Wikipedia

    en.wikipedia.org/wiki/Critical_Assessment_of...

    The Critical Assessment of Functional Annotation (CAFA) is an experiment designed to provide a large-scale assessment of computational methods dedicated to predicting protein function. [1] Different algorithms are evaluated by their ability to predict the Gene Ontology (GO) terms in the categories of Molecular Function , Biological Process ...

  7. Metatranscriptomics - Wikipedia

    en.wikipedia.org/wiki/Metatranscriptomics

    Metatranscriptomics is the set of techniques used to study gene expression of microbes within natural environments, i.e., the metatranscriptome. [1]While metagenomics focuses on studying the genomic content and on identifying which microbes are present within a community, metatranscriptomics can be used to study the diversity of the active genes within such community, to quantify their ...

  8. List of sequence alignment software - Wikipedia

    en.wikipedia.org/wiki/List_of_sequence_alignment...

    Slider is an application for the Illumina Sequence Analyzer output that uses the "probability" files instead of the sequence files as an input for alignment to a reference sequence or a set of reference sequences. Yes Yes No No [53] [54] 2009-2010 SOAP, SOAP2, SOAP3, SOAP3-dp SOAP: robust with a small (1-3) number of gaps and mismatches.

  9. Klenow fragment - Wikipedia

    en.wikipedia.org/wiki/Klenow_fragment

    The Klenow fragment is a large protein fragment produced when DNA polymerase I from E. coli is enzymatically cleaved by the protease subtilisin.First reported in 1970, [1] it retains the 5' → 3' polymerase activity and the 3’ → 5’ exonuclease activity for removal of precoding nucleotides and proofreading, but loses its 5' → 3' exonuclease activity.

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